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Fluoxetine (generic for Prozac) is one of so called selective serotonin reuptake inhibitors (SSRIs). This group of drugs also includes citalopram (Celexa), escitalopram (Lexapro), fluvoxamine (Luvox, Luvox CR), paroxetine (Paxil), and sertraline (Zoloft).
Prozac has been approved in 1987. Over 22.2 million prescriptions for generic formulations of fluoxetine were filled in the United States in 2007, so it became the third most prescribed antidepressant.
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